Publications in scientific journals: 2019

Research based on NTR data

2019

Abdellaoui A, Chen HY, Willemsen G, Ehli EA, Davies GE, Verweij KJH, Nivard MG, Geus EJC de, Boomsma DI, Cacioppo JT. Associations between Loneliness and Personality are Mostly Driven by a Genetic Association with Neuroticism. Journal of Personality. 2019;87(2):386-397
DOI: 10.1111/jopy.12397

Abdellaoui A, Sanchez-Roige S, Sealock J, Treur JL, Dennis J, Fontanillas P, Elson S, the 23andMe Research Team, Nivard MG, Ip HF, Zee MD van der, Baselmans BML, Hottenga JJ, Willemsen G, Mosing M, Lu Y, Pedersen NL, Denys D, Amin N, Duijn CM van, Szilagyi I, Tiemeier H, Neumann A, Verweij KJH, Cacioppo S, Cacioppo JT, Davis LK, Palmer AA, Boomsma DI. Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness. Human Molecular Genetics. 2019;28(22):3853-3865, Open Access
DOI: 10.1093/hmg/ddz219
Supplementary Materials (zip file)

Allegrini AG, Verweij KJH, Abdellaoui A, Treur JL, Hottenga JJ, Willemsen G, Boomsma DI, International Cannabis Consortium, Vink JM. Genetic vulnerability for smoking and cannabis use: associations with e-cigarette and water pipe use. Nicotine & Tobacco Research. 2019;21(6):723-730
DOI: 10.1093/ntr/nty150
Supplementary Materials (zip file)

Arias-Vasquez A, Groffen AJ, Spijker S, Ouwens KG, Klein M, Vojinovic D, Galesloot TE, Bralten J, Hottenga JJ, Most PJ van der, Kattenberg VM, Pool R, Nolte IM, Penninx BWJH, Fedko IO, Dolan CV, Nivard MG, Braber A den, Duijn CM van, Hoekstra PJ, Buitelaar JK, Kiemeney LA, Hoogman M, Middeldorp CM, Draisma HHM, Vermeulen SH, Sánchez-Mora C, Ramos-Quiroga JA, Ribasés M, The EAGLE-ADHD Consortium, Hartman CA, Kooij JJS, Amin N, Smit AB, Franke B, Boomsma DI. A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms. Behavior Genetics. 2019;49(3):270-285
DOI: 10.1007/s10519-018-09947-2
Supplementary Materials (zip file)

Baselmans BML, Jansen R, Ip HF, Dongen J van, Abdellaoui A, Weijer MP van de, Bao Y, Smart M,  Kumari M, Willemsen G, Hottenga JJ, BIOS Consortium, Social Science Genetic Association Consortium, Boomsma DI, Geus EJC de, Nivard MG, Bartels M. Multivariate genome-wide analyses of the well-being spectrum. Nature Genetics. 2019;51(3):445-451
DOI: 10.1038/s41588-018-0320-8
Supplementary Materials (zip file)

Baselmans BML, Weijer MP van de, Abdellaoui A, Vink JM, Hottenga JJ, Willemsen G, Nivard MG, Geus EJC de, Boomsma DI, Bartels M. A Genetic Investigation of the Well-Being Spectrum. Behavior Genetics. 2019;49(3):286-297, Open Access
DOI: 10.1007/s10519-019-09951-0
Supplementary Materials (zip file)

Beck JJ, Hottenga JJ, Mbarek H, Finnicum CT, Ehli EA, Hur YM, Martin NG, Geus EJC de, Boomsma DI,  Davies GE. Genetic Similarity Assessment of Twin-Family Populations by Custom-Designed Genotyping Array. Twin Research and Human Genetics. 2019;22(4):210-219
DOI: 10.1017/thg.2019.41
Supplementary Materials (zip file)

Bouma MJ, Freund C, IJzerman AP, Boomsma DI, Mummery CL, Raymond K. Lymphoblast-derived hiPS cell lines generated from four individuals of a family of genetically unrelated parents and their female monozygotic twins. Stem Cell Research. 2019;41(101654), Open Access
DOI: 10.1016/j.scr.2019.101654
Supplementary Materials (zip file)

Czamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O'Donnell KJ, Garg E, Meaney MJ, Entringer S, Wadhwa PD, Buss C, Jones MJ, Lin DTS, MacIsaac JL, Kobor MS, Koen N, Zar HJ, Koenen KC, Dalvie S, Stein DJ, Kondofersky I, Müller NS, Theis FJ, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui A, Dolan CV, Hottenga JJ, Mbarek H, Middeldorp CM, Nivard MG, Willemsen G, Boomsma DI, Geus EJC de, Räikkönen K, Binder EB, many others. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications. 2019;10(2548), Open Access
DOI: 10.1038/s41467-019-10461-0
Supplementary Materials (zip file)

Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, Davies GE, Ehli EA, Fedko IO, Groen-Blokhuis MM, Hammerschlag AR, Hottenga JJ, Hudziak JJ, Ouwens KG, 23andMe Research Team, Boomsma DI, Middeldorp CM, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge, Mors O, Bo Mortensen P, Daly MJ, Faraone SV, Børglum AD, Neale BM, many others. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics. 2019;51(1):63-75
DOI: 10.1038/s41588-018-0269-7
Supplementary Materials (zip file)

Derks IPM, Bolhuis K, Yalcin Z, Gaillard R, Hillegers MHJ, Larsson H, Lundström S, Lichtenstein, Beijsterveldt CEM van, Bartels M, Boomsma DI, Tiemeier H, Jansen PW. Testing Bidirectional Associations Between Childhood Aggression and BMI: Results from Three Cohorts. Obesity. 2019;27(5):822-829, Open Access
DOI: 10.1002/oby.22419
Supplementary Materials (zip file)

Doering S, Lichtenstein P, Gillberg C, Boomsma DI, Beijsterveldt CEM van, Ligthart L, Willemsen G, Geus EJC de, Middeldorp CM, Bartels M, Kuja-Halkola R, Lundström S. Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies. BMC Psychiatry. 2019;19(363), Open Access
DOI: 10.1186/s12888-019-2349-3
Supplementary Materials (zip file)

Dongen J van, Zilhão NR, Sugden K, BIOS Consortium, Hannon EJ, Mill J, Caspi A, Agnew-Blais J, Arseneault L, Corcoran DL, Moffitt TE, Poulton R, Franke B, Boomsma DI. Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry. 2019;86(8):599-607, Open Access
DOI: 10.1016/j.biopsych.2019.02.016
Supplementary Materials (zip file)

Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Rüschendorf F, the 23andMe Research Team, collaborators of the SHARE study, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jorgenson E, Lee YA, Boomsma DI, Karlsson R, Almqvist C, Koppelman GH, Paternoster L. Eleven loci with new reproducible genetic associations with allergic disease risk. Journal of Allergy and Clinical Immunology. 2019;143(2):691-699
DOI: 10.1016/j.jaci.2018.03.012
Supplementary Materials (zip file)

Finnicum CT, Beck JJ, Dolan CV, Davis C, Willemsen G, Ehli EA, Boomsma DI, Davies GE, Geus EJC de. Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk. BMC Microbiology. 2019;19(230), Open Access
DOI: 10.1186/s12866-019-1602-8
Supplementary Materials (zip file)

Generaal E, Hoogendijk EO, Stam M, Henke CE, Rutters F, Oosterman M, Huisman M, Kramer SE, Elders PJM, Timmermans EJ, Lakerveld J, Koomen E, Have M ten, Graaf R de, Snijder MB, Stronks K, Willemsen G, Boomsma DI, Smit JH, Penninx BWJH. Neighbourhood characteristics and prevalence and severity of depression: pooled analysis of eight Dutch cohort studies. The British Journal of Psychiatry. 2019;215(2):468-475, Open Access
DOI: 10.1192/bjp.2019.100
Supplementary Materials (zip file)

Gupta R, Dongen J van, Fu Y, Abdellaoui A, Tyndale RF, Velagapudi V, Boomsma DI, Korhonen T, Kaprio J, Loukola A, Ollikainen M. Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci. Clinical Epigenetics. 2019;11(1), Open Access
DOI: 10.1186/s13148-018-0606-9
Supplementary Materials (zip file)

Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, 23and Me Research Team, eQTLGen Consortium, Jansen R, Penninx BWJH, Dongen J van, International Cannabis Consortium, Social Science Genetic Association Consortium, Gupta R, Peyrot WJ, Hottenga JJ, Vinkhuyzen AAE, Willemsen G, Dolan CV, Boomsma DI, Posthuma D, Tiemeier H, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger PD, Beauchamp JP, many others. Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics. 2019;51(2):245-257
DOI: 10.1038/s41588-018-0309-3
Supplementary Materials (zip file)

Kochunov P, Patel B, Ganjgahi H, Donohue B, Ryan M, Hong EL, Chen X, Adhikari B, Jahanshad N, Thompson PM, Ent D van't, Braber A den, Geus EJC de, Brouwer RM, Boomsma DI, Hulshoff Pol HE, Zubicaray GI de, McMahon KL, Martin NG, Wright MJ, Nichols TE. Homogenizing Estimates of Heritability Among SOLAR-Eclipse, OpenMx, APACE, and FPHI Software Packages in Neuroimaging Data. Frontiers in Neuroinformatics. 2019;13(16), Open Access
DOI: 10.3389/fninf.2019.00016

Konijnenberg E, Braber A den, Kate M ten, Tomassen J, Mulder SD, Yaqub M, Teunissen CE, Lammertsma AA, Berckel BNM van, Scheltens P, Boomsma DI, Visser PJ. Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults: a monozygotic twin study. Neurobiology of Aging, 77:58-65, Open Access
DOI: 10.1016/j.neurobiolaging.2019.01.006
Supplementary Materials (zip file)

Kreeke JA van de, Nguyen HT, Haan J den, Konijnenberg E, Tomassen J, Braber A den, Kate M ten, Collij L, Yaqub M, Berckel B van, Lammertsma AA, Boomsma DI, Stevie Tan H, Verbraak FD, Visser PJ. Retinal layer thickness in preclinical Alzheimer’s disease. Acta Ophthalmologica. 2019;97(8):798-804, Open Access
DOI: 10.1111/aos.14121

Küpers LK, C Monnereau, GC Sharp, P Yousefi, LA Salas, A Ghantous, CM Page, SE Reese, AJ Wilcox, D Czamara, J van Dongen, G Willemsen, H Mbarek, DI Boomsma, EB Binder, G Davey Smith, VWV Jaddoe, RT Lie, W Nystad, SJ London, DA Lawlor, CL Relton, H Snieder, JF Felix, many others. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nature Communications. 2019;10(1):1893, Open Access
DOI: 10.1038/s41467-019-09671-3
Supplementary Materials (zip file)

Lee PH, Anttila V, Won H, Feng YCA, Rosenthal J, Zhu Z, Tucker-Drob EM, Nivard MG, Grotzinger AD, Posthuma D, Derks EM, Slof-Op’t Landt MCT, Boomsma DI, Geus EJC de, Hottenga JJ, Mbarek H, Middeldorp CM, Penninx BWJH, Cath DC, Denys D, Santangelo SL, Scharf JM, Stein MB, Thornton LM, Walters JTR, Wray NR, Geschwind DH, Neale BM, Kendler KS, Smoller JW, many others. Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell, 179(7):1469-1482
DOI: 10.1016/j.cell.2019.11.020
Supplementary Materials (zip file)

Ligthart L, Beijsterveldt CEM van, Kevenaar ST, Zeeuw E de, Bergen E van, Bruins S, Pool R, Helmer Q, Dongen J van, Hottenga JJ, Ent D van’t, Dolan CV, Davies GE, Ehli EA, Bartels M, Willemsen G, Geus EJC de, Boomsma DI. The Netherlands Twin Register: Longitudinal Research Based on Twin and Twin-Family Designs. Twin Research and Human Genetics. 2019;22(6):626-636, Open Access
DOI: 10.1017/thg.2019.93

Liu J, Carnero-Montoro E, Dongen J van, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Willemsen G, Geus EJC de, Hivert MF, Rotter JI, Meigs JB, Pankow JS, Meurs JBJ van, Isaacs A, Boomsma DI, Bell JT, Demirkan A, Duijn CM van, many others. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications. 2019;10(2581), Open Access
DOI: 10.1038/s41467-019-10487-4
Supplementary Materials (zip file)

Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, 23andMe Research Team, HUNT All-In Psychiatry, Hottenga JJ, Willemsen G, Boomsma DI, Davies GE, Polderman TJC, Posthuma D, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S, many others. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature Genetics. 2019;51(2):237-244
DOI: 10.1038/s41588-018-0307-5
Supplementary Materials (zip file)

Luningham JM, McArtor DB, Hendriks AM, Beijsterveldt CEM van, Lichtenstein P, Lundström S, Larsson H, Bartels M, Boomsma DI, Lubke GH. Data Integration Methods for Phenotype Harmonization in Multi-Cohort Genome-Wide Association Studies With Behavioral Outcomes. Frontiers in Genetics. 2019;10:1227, Open Access
DOI: 10.3389/fgene.2019.01227
Supplementary Materials (zip file)

Maas SCE,  Vidaki A, Wilson R, Teumer A, Liu F, Meurs JBJ van, Uitterlinden AG, Boomsma DI, Geus EJC de, Willemsen G, Dongen J van, Kallen CJH van der, Slagboom PE, Beekman M, HeemstD van, Berg LH van den, BIOS Consortium, Duijts L, Jaddoe VWV, Ladwig KH, Kunze S, Peters A, Ikram MA, Grabe HJ, Felix JF, Waldenberger M, Franco OH, Ghanbari M, Kayser M. Validated inference of smoking habits from blood with a finite DNA methylation marker set. European Journal of Epidemiology. 2019;34(11):1055-1074, Open Access
DOI: 10.1007/s10654-019-00555-w
Supplementary Materials (zip file)

Malanchini M, Smith-Woolley E, Ayorech Z, Rimfeld K, Krapohl E, Vuoksimaa E, Korhonen T, Bartels M, Beijsterveldt CEM van, Rose RJ, Lundström S, Anckarsäter H, Kaprio J, Lichtenstein P, Boomsma DI, Plomin R. Aggressive behaviour in childhood and adolescence: the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium. Psychological Medicine. 2019;49(4):646-654, Open Access
DOI: 10.1017/S0033291718001344
Supplementary Materials (zip file)

Mbarek H, Weijer MP van de, Zee MD van der, Ip HF, Beck JJ, Abdellaoui A, Ehli EA, Davies GE, Baselmans BML, Nivard MG, Bartels M, Geus EJC de, Boomsma DI. Biological insights into multiple birth: genetic findings from UK Biobank. European Journal of Human Genetics. 2019;27(6):970-979
DOI: 10.1038/s41431-019-0355-z
Supplementary Materials (zip file)

Mbarek H, Beijsterveldt CEM van, Hottenga JJ, Dolan CV, Boomsma DI, Willemsen G, Vink JM. Association between rs1051730 and smoking during pregnancy in Dutch women. Nicotine & Tobacco Research. 2019;21(6):835-840
DOI: 10.1093/ntr/ntx267
Supplementary Materials (zip file)

Middeldorp CM, Felix JF, Mahajan A, EArly Genetics Lifecourse Epidemiology (EAGLE) consortium, Early Growth Genetics (EGG) Consortium, Bartels M, Davies GE, Fedko IO, Hottenga JJ, Mbarek H, Nivard MG, Beijsterveldt CEM van, Willemsen G, Perry JRB, Grant SFA, Boomsma DI, Freathy RM, McCarthy MI, many others. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. European Journal of Epidemiology. 2019;34(3):279-300, Open Access
DOI: 10.1007/s10654-019-00502-9

Milaneschi Y, Peyrot WJ, Nivard MG, Mbarek H, Boomsma DI, Penninx BWJH. A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics. Translational Psychiatry. 2019;9(219), Open Access
DOI: 10.1038/s41398-019-0554-y
Supplementary Materials (zip file)

Moore R, Casale FP, Bonder MJ, Horta D, BIOS Consortium, Boomsma DI, Pool R, Dongen J van, Hottenga JJ, Franke L, Barroso I, Stegle O, many others. A linear mixed-model approach to study multivariate gene–environment interactions. Nature Genetics. 2019;51(1):180-186
DOI: 10.1038/s41588-018-0271-0
Supplementary Materials (zip file)

Nersisyan L, Nikoghosyan M, The Genome of the Netherlands Consortium, Abdellaoui A, Hottenga JJ, Kattenberg M, Willemsen G, Boomsma DI, Arakelyan A, many others. WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene. Nature Scientific Reports. 2019;9(18758), Open Access
DOI: 10.1038/s41598-019-55109-7
Supplementary Materials (zip file)

Odintsova VV, Dolan CV, Beijsterveldt CEM van, Zeeuw EL de, Dongen J van, Boomsma DI. Pre- and Perinatal Characteristics Associated with Apgar Scores in a Review and in a New Study of Dutch Twins. Twin Research and Human Genetics. 2019;22(3):164-176, Open Access
DOI: 10.1017/thg.2019.24
Supplementary Materials (zip file)

Odintsova VV, Roetman PJ, Ip HF, Pool R, Laan CM van der, Tona KD, Vermeiren RRJM, Boomsma DI. Genomics of human aggression: current state of genomewide studies and an automated systematic review tool. Psychiatric Genetics, 29(5):170-190, Open Access
DOI: 10.1097/YPG.0000000000000239
Supplementary Materials (zip file)

Odintsova VV, Hagenbeek FA, Suderman M, Caramaschi D, Beijsterveldt CEM van, Kallsen NA, Ehli EA, Davies GE, Sukhikh GT, Fanos V, Relton C, Bartels M, Boomsma DI, Dongen J van. DNA Methylation Signatures of Breastfeeding in Buccal Cells Collected in Mid-Childhood. Nutrients, 11(11):2804, Open Access
DOI: 10.3390/nu11112804
Supplementary Materials (zip file)

Onderwater GLJ, Ligthart L, Bot M, Demirkan A, Fu J, Kallen CJH van der, Vijfhuizen LS, Pool R, Liu J, Vanmolkot FHM, Beekman M, Wen K, Amin N, Thesing CS, Pijpers JA, Kies DA, Zielman R, Boer I de, Greevenbroek MMJ van, Arts ICW, Milaneschi Y, Schram MT, Dagnelie PC, Franke L, Arfan Ikram M, Ferrari MD, Goeman JJ, Slagboom PE, Wijmenga C, Stehouwer CDA, Boomsma DI, Duijn CM van, Penninx BWJH, Hoen PAC ’t, Terwindt GM, Maagdenberg, BBMRI Metabolomics Consortium. Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology. 2019;92(16):e1899-e1911, Open Access
DOI: 10.1212/WNL.0000000000007313

Polimanti R, Peterson RE, Ong JS, Macgregor S, Edwards AC, Clarke TK, Frank J, Gerring Z, Gillespie NA, Lind PA, Maes HH, Martin NG, Mbarek H, Medland SE, Streit F, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui A, Dolan CV, Hottenga JJ, Jansen R, Middeldorp CM, Nivard MG, Peyrot WJ, Posthuma D, Willemsen G, Boomsma DI, Geus EJC de, Penninx BWJH, Ligthart L, 23andMe Research Team, Agrawal A, Edenberg HJ, Kendler KS, Lewis CM, Sullivan PF, Wray NR, Gelernter J, Derks EM, many others. Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. Psychological Medicine. 2019;49(7):1218-1226
DOI: 10.1017/S0033291719000667
Supplementary Materials (zip file)

Porcu E, Rüeger S, Lepik K, eQTLGen Consortium, Boomsma DI, Nivard MG, Dongen J van, BIOS Consortium, Hottenga JJ, Pool R, Santoni FA, Reymond A, Kutalik Z, many others. Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications. 2019;10(3300), Open Access
DOI: 10.1038/s41467-019-10936-0
Supplementary Materials (zip file)

Rooij J van, Mandaviya PR, Claringbould A, Felix JF, Dongen J van, Jansen R, Franke L, BIOS consortium, Hoen PAC ’t, Heijmans B, Meurs JBJ van. Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies. Genome Biology. 2019;20:235, Open Access
DOI: 10.1186/s13059-019-1878-x
Supplementary Materials (zip file)

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Braber A den, Milaneschi Y, Boomsma DI, Davies GE, Penninx BWJH, Geus EJC de, Hottenga JJ, Hulshoff Pol HE, Fedko IO, Ent D van ’t, DeCarli C, Jager PL de, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA, many others. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. 2019;51(11):1624-1636
DOI: 10.1038/s41588-019-0511-y
Supplementary Materials (zip file)

Schutte NM, Nederend I, Bartels M, Geus EJC de. A twin study on the correlates of voluntary exercise behavior in adolescence. Psychology of Sport and Exercise. 2019;40:99-109
DOI: 10.1016/j.psychsport.2018.10.002

Setten J van, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I, Grarup N, Hall LM, Boomsma DI, Hottenga JJ, Samani NJ, Sotoodehnia N, Ulivi S, Wilson JG, Geus EJC de, Jukema JW, Stricker B B, Harst P van der, Bakker PIW de, Isaacs A, many others. Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics. 2019;27(6):952-962, Open Access
DOI: 10.1038/s41431-018-0295-z
Supplementary Materials (zip file)

Shvetsova E, Sofronova A, Monajemi R, Gagalova K, Draisma HHM, White SJ, Santen GWE, Chuva de Sousa Lopes SM, Heijmans BT, Meurs J van, Jansen R, Franke L, Kielbasa SM, Dunnen JT den, Hoen PAC 't, BIOS Consortium, GoNL consortium, Boomsma DI, Pool R, Dongen J van, Hottenga JJ, Abdellaoui A, Willemsen G, many others. Skewed X-inactivation is common in the general female population. European Journal of Human Genetics. 2019;27(3):455-465, Open Access
DOI: 10.1038/s41431-018-0291-3
Supplementary Materials (zip file)

Silventoinen K, Jelenkovic A, Latvala A, Yokoyama Y, Sund R, Sugawara M, Tanaka M, Matsumoto S, Aaltonen S, Piirtola M, Willemsen G, Bartels M, Beijsterveldt CEM van, Tucker-Drob EM, Franz CE, Kremen WS, Lyons MJ, Lichtenstein P, Jeong HU, Hur YM, Boomsma DI, Sørensen TIA, Kaprio J, many others. Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts. Obesity. 2019;27(5):855-865, Open Access
DOI: 10.1002/oby.22451
Supplementary Materials (zip file)

Silventoinen K, Jelenkovic A, Yokoyama Y, Sund R, Sugawara M, Tanaka M, Matsumoto S, Bogl LH, Freitas DL, Maia JA, Willemsen G, Bartels M, Beijsterveldt CEM van, Llewellyn CH, Fisher A, Rebato E, Busjahn A, Tomizawa R, Inui F, Watanabe M, Honda C, Sakai N, Hur YM, Sørensen TIA, Boomsma DI, Kaprio J, many others. The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins. Twin Research and Human Genetics. 2019;22(6):800-808
DOI: 10.1017/thg.2019.35

Spek A van der, Broer L, Draisma HHM, Pool R, Albrecht E, Beekman M, Mangino M, Raag M, Nyholt DR, Dharuri HK, Codd V, Amin N, Geus EJC de, Deelen J, Demirkan A, Yet I, Fischer K, Haller T, Henders AK, Isaacs A, Medland SE, Montgomery GW, Mooijaart SP, Strauch K, Suchiman HED, Vaarhorst AAM, Heemst D van, Wang-Sattler R, Whitfield JB, Willemsen G, Wright MJ, Martin NG, Samani NJ, Metspalu A, Slagboom PE, Spector TD, Boomsma DI, Duijn CM van, Gieger C. Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. Nature Scientific Reports. 2019;9:11623, Open Access
DOI: 10.1038/s41598-019-47282-6
Supplementary Materials (zip file)

Teeuw J, Brouwer RM, Koenis MMG, Swagerman SC, Boomsma DI, Hulshoff Pol HE. Genetic Influences on the Development of Cerebral Cortical Thickness During Childhood and Adolescence in a Dutch Longitudinal Twin Sample: The Brainscale Study. Cerebral Cortex. 2019;29(3):978-993, Open Access
DOI: 10.1093/cercor/bhy005
Supplementary Materials (zip file)

Teeuw J, Brouwer RM, Guimarães JPOFT, Brandner P, Koenis MMG, Swagerman SC, Verwoert M, Boomsma DI, Hulshoff Pol HE. Genetic and environmental influences on functional connectivity within and between canonical cortical resting-state networks throughout adolescent development in boys and girls. NeuroImage. 2019;202:116073, Open Access
DOI: 10.1016/j.neuroimage.2019.116073
Supplementary Materials (zip file)

Timmers PR, Mounier N, Lall K, Fischer K, Ning Z, Feng X, Bretherick AD, Clark DW, eQTLGen Consortium, Boomsma DI, Dongen J van, Jansen R, Nivard MG, Penninx BWJH, Shen X, Esko T, Kutalik Z, Wilson JF, Joshi PK, many others. Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. eLIFE. 2019;8(e39856)
DOI: 10.7554/eLife.39856

Vanbinst K, Bergen E van, Ghesquière P, De Smedt B. Cross-domain associations of key cognitive correlates of early reading and early arithmetic in 5-year-olds. Early Childhood Research Quarterly. 2019;51:144-152
DOI: 10.1016/j.ecresq.2019.10.009

Vandenbosch MMLJZ, Ent D van 't, Boomsma DI, Anokhin AP, Smit DJA. EEG-based age-prediction models as stable and heritable indicators of brain maturational level in children and adolescents. Human Brain Mapping. 2019;40(6):1919-1926, Open Access
DOI: 10.1002/hbm.24501
Supplementary Materials (zip file)

Veldkamp SAM, Boomsma DI, Zeeuw EL de, Beijsterveldt CEM van, Bartels M, Dolan CV, Bergen E van. Genetic and Environmental Influences on Different Forms of Bullying Perpetration, Bullying Victimization, and Their Co-occurrence. Behavior Genetics. 2019;49(5):432-443, Open Access
DOI: 10.1007/s10519-019-09968-5
Supplementary Materials (zip file)

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Li-Gao R, Hottenga JJ, Consortium EGG, Willemsen G, Mbarek H, Beijsterveldt CEM van, Bartels M, Vrijkotte TGM, Geus EJC de, Boomsma DI, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JRB, Evans DM, Freathy RM, many others. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. 2019;51(5):804-814
DOI: 10.1038/s41588-019-0403-1
Supplementary Materials (zip file)

Willems YE, Boesen N, Li J, Finkenauer C, Bartels M. The heritability of self-control: A meta-analysis. Neuroscience & Biobehavioral Reviews. 2019;100:324-334, Open Access
DOI: 10.1016/j.neubiorev.2019.02.012
Supplementary Materials (zip file)

Zee MD van der, Mee D van der, Bartels M, Geus EJC de. Tracking of voluntary exercise behaviour over the lifespan. International Journal of Behavioral Nutrition and Physical Activity. 2019;16:17, Open Access
DOI: 10.1186/s12966-019-0779-4
Supplementary Materials (zip file)

Zeeuw EL de, Kan KJ, Beijsterveldt CEM van, Mbarek H, Hottenga JJ, Davies GE, Neale MC, Dolan CV, Boomsma DI. The moderating role of SES on genetic differences in educational achievement in the Netherlands. NPJ Science of Learning. 2019;4:13, Open Access
DOI: 10.1038/s41539-019-0052-2

Zhang X, Abdellaoui A, Rucker J, Jong S de, Potash JB, Weissman MM, Shi J, Knowles JA, Pato C, Pato M, Sobell J, Smit JH, Hottenga JJ, Geus EJC de, Lewis CM, Buttenschøn HN, Craddock N, Jones I, Jones L, McGuffin P, Mors O, Owen MJ, Preisig M, Rietschel M, Rice JP, Rivera M, Uher R, Gejman PV, Sanders AR, Boomsma DI, Penninx BWJH, Breen G, Levinson DF. Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biological Psychiatry. 2019;85(12):1065-1073, Open Access
DOI: 10.1016/j.biopsych.2019.02.022
Supplementary Materials (zip file)